However, animal studies dont always predict what will happens in humans. These tests will look at your cholesterol levels and also your liver enzyme levels. (For information on side effects, see the Zetia side effects section above.). The heart beats faster to pump it up to the brain, but with little success. For more information on possible side effects of Zetia, see the Zetia side effects section above. * For these purposes, Zetia and Crestor are used to treat people of different ages. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Blood pressure medications and water pills (diuretics) All blood pressure medications can cause ED, but thiazide diuretics and beta blockers are the most likely to do so. If your liver function tests show increased liver enzymes called transaminases while youre using Zetia with a statin drug, your doctor may stop your treatment. tender, swollen glands in neck. They can give you tips on how to deal with any side effects that may be bothersome. POTS is defined by its particular symptoms and an excessive increase in heart rate upon standing. Here we look at how Zetia and Crestor are alike and different. Zetia is FDA-approved to treat certain forms of high cholesterol in adults and children. Its intestinal molecular target is the Niemann-Pick C1-Like 1 (NPC1L1) sterol transporter. To determine whether you have high cholesterol, your doctor will do a blood test called a lipid panel. Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. What causes POTS? (For more information on the specific conditions Zetia can treat, see the Zetia uses section.). Crossing your legs in front of each other while standing, rocking up and down on your toes. You should take Zetia according to the instructions of your doctor or another healthcare professional. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). How long a medication remains good can depend on many factors, including how and where you store the medication. And some may be easily managed, too. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. As patients we need to be constantly wary because it is increasingly clear that the pharmas have abrogated their responsibility on our behalf. Statins are drugs used to lower cholesterol. Risk factors for muscle-related problems. These problems can include muscle pain and muscle weakness, and rarely, muscle breakdown. 6. There arent any foods that have been specifically reported to interact with Zetia. If you need financial support to pay for Zetia, or if you need help understanding your insurance coverage, help is available. Zinnia elegans 'Benary's Giant Golden Yellow'. Call 911 or your local emergency number if your symptoms feel life threatening or if you think youre having a medical emergency. In people with POTS, more blood collects in the lower body when standing upright. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. Have your doctor measure your heart rate sitting and standing. However, studies have found both Zetia and Lipitor to be effective for lowering cholesterol. This helps prevent others, including children and pets, from taking the drug by accident. If you have questions about the differences between Zetia and statin drugs, talk with your doctor. People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. No, hair loss isnt a known side effect of Zetia. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. However, 0.5% of adults and children who took Zetia with a statin drug experienced muscle pain so bothersome that they had to stop treatment. Zetia contains the active drug ezetimibe. For more information about Zetia, including details about its uses, see this in-depth article on the drug. Fenofibrate belongs to the fibrate drug class. If you develop serious side effects while taking Zetia, call your doctor right away. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre using Zetia. You should store Zetia tablets at a room temperature of 77F (25C) in a tightly sealed container away from light. Like most drugs, Zetia can cause an allergic reaction in some people. Your doctor will determine the best dosage to fit your needs. It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. Its primary metabolic pathway is via hepatic glucuronic conjunction. Zetia is indicated as an adjunct to a low-cholesterol diet for treatment of the following types of hyperlipidemia: For treatment of primary hyperlipidemia, Zetia is indicated to reduce total cholesterol, low-density lipoprotein (LDL) cholesterol, non-high-density lipoprotein (non-HDL) cholesterol, and apiloprotein B (ApoB). Youll also need to check your insurance plan, as it may only cover one or the other. However, several medicines can be prescribed off-label when needed. Statin drugs may pass into breast milk. The heartbeat increases with a feeling of the heart fluttering. But if they become more severe or dont go away, talk with your doctor or pharmacist. During Zetia treatment, your doctor will likely recommend blood tests. Zetia should be protected from moisture and shouldnt be stored in areas where it could get damp or wet, such as bathrooms. Zetia may stay in your system for several days after you stop taking it. Below are examples of these side effects. The generic is considered to be as safe and effective as the original drug. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. Porphyria patients are often overly sensitive to sunlight. You should always consult your doctor or another healthcare professional before taking any medication. Ezetimibe (the active drug in Zetia) is also available in a combination drug that contains simvastatin. Fatigue. zetia. Common side effects may include: diarrhea; cold symptoms such as stuffy nose, sneezing, sore throat; pain in an arm or leg; joint pain; or. Its not clear if CoQ10 prevents muscle-related side effects when Zetia is taken with a statin, but it might help. Use these discussion points about familial hypercholesterolemia to prepare for your doctors appointment. OI is a condition in which an excessively reduced volume of blood returns to the heart after an individual stands up from a lying down position. Can diet help improve depression symptoms? They may have suggestions depending on your weight and health goals. Legal news and analysis on health care, hospitals, insurers, medical suppliers. If you have questions about weight changes while using Zetia, talk with your doctor. Heres some detail on certain side effects this drug may or may not cause. However, if youre taking Zetia with a statin drug, youll need to avoid eating grapefruit or drinking grapefruit juice. Zetias effect on cardiovascular morbidity and mortality isnt known. Your body uses cholesterol to make some vitamins, hormones, and fluids that help you digest food. A large review by the American Heart Association compared studies of CoQ10. Statins shouldnt be used during pregnancy. Crestor is part of the statin drug class. Lipitor is part of the statin drug class. The manufacturer of Zetia hasnt stated whether the tablets can be crushed, split, or chewed. These symptoms can be signs of an infection. Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. If you have high cholesterol with hypertension (high blood pressure) or diabetes, youll likely have to take other drugs with Zetia to treat these conditions. Recently, POTS has been diagnosed in some people who have had COVID-19. Zetia is also available in a generic form called ezetimibe. Sharing this information can help you avoid potential interactions. Read on to find out more about healthy cholesterol levels, and if a cholesterol level of 250 ml/dL is considered, Heart disease is a top cause of death in the U.S. Females who could become pregnant should use birth control while taking Zetia with a statin drug. . Increased liver enzyme levels are a possible side effect of Zetia. Study on Ezetimibe Yielded Disappointing Results: Another reader wrote us shortly after learning of the results of a study that raised questions about ezetimibe: Q. 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