I just hope and pray she gets better. In total we spend around $780 trying to control/stop the tremors & seizures. I will never give him this drug again. Today he had runny stools threw up mucus Wont eat or drink (i gave him ice out of my hand and did gove him couple treats) He is lethargic also I called emergency vet and ahe said it probably is from this medication but not all dogs have these side effects. I hope yours is an isolated incident! My husband said , get dressed were taking him in . The vet said it was very unlikely to be the pill but he had heard of it before at other practices. She keeps running through the house as though looking for something. I was reading that this drug enters the bloodstream quickly after giving it, and these symptoms and all the other reports have convinced me that I'm done using this on my pup. She has good days and bad days but she is far from the dog she use to be. I wish I would have came across this before I gave my healthy 9 month old puppy this medication two days ago. He lays on his bed tucked far in the corner. He is pissing a lot and often and drinking a lot of water. They immediately denied they were in the wrong for prescribing because any meds can have side effects but Im convinced this medication is poison. Certain age, breed predispositions. Im wondering if anyone else has seen these types of symptoms. About 11 months ago our vet recommended Simparica Trio. Revolution has been around decades with less incidents of animal reactions. Were now into day 2 no changes except add a continuous walking into the next room turn around come back sit down just to repeat several more times. Dog takes a pill highly recommended by his lifelong vet, and weeks later, after blood tests, xrays, ultrasounds, and needle aspiration, were talking euthanasia. Shame on you! Our new vet has recommended Simperica, but I wont be giving it to my Collie. These dog training tips will help you get started. Hi there, So sorry to hear about your dog. The doctor did blood work and gave him steroids and said to watch him carefully for the next few days. Our 3 mo.old Boston Terrier, 10 lbs, had her first dose of Simparaco yesterday. She probabpy had some in her system (which is quite common, even for well-cated-for puppies), which would explain her diarrhea. I can not find any information on a delayed reaction AND my Vet just discredits that its the Simparica because my dog goes to Daycare and could be exposed to other mystery things. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. What are the side effects of Simparica Trio Chewable Tablets for Dogs? Considerations Just like any other medication, Simparica has the potential to interact with other drugs your dog is taking. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. They have become so bad that she cries and whimpers any time she is laying down. If this is a long term issue, I doubt they would be willing to cover all visits in the future. We were so upset - I vowed to never use oral flea treatment again. I realized he had no control over his body . My dog was super sick the first months of his life. In general dogs tolerate very well sarolaner at the therapeutic dose range (2 to 4 mg/kg). Neurologist doesnt seem to really know if the effects are long term or not. The American Heartworm Society recommends year-round heartworm prevention for all dogs in the United States, and the Companion Animal Parasite Council recommends broad-spectrum parasite control to prevent heartworms, intestinal parasites, fleas, and ticks for all dogs in North America. My 2 year old Shepherd was perfectly healthy in Feb. and by April of this year he quit eating, excessive thirst, excessive urination, low platelet count, low red blood cell count is unsteady and now is at a vet hospital and so far we have spent 2000 and they do not know what is wrong with him. The vet suggested this medication for my 9+ yr old English Bulldog. Although the mother that took the same had not shown any effects. Your vet should be able to answer any questions related to side effects, precautions, or special care for your dog. I did not notice any side effects. Thank you in advance. Today she has fallen 2 or 3 times in the last 8 hours). I must admit that I am pretty nervous about it, but we shall see. The very next day he had diarrhea, and had it for 6 days. Its Sunday night and still vomiting. Another call to vet asking for an appt - seems like an an emergency now? Gave our 23 month old Black Lab. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. In the meantime i keep trying to give him ice and i am very worried that i have permanently harmed him. Other adverse reactions like lethargy, anorexia, itching, and increased thirst are possible but not very likely. Hi, Id like to thank all the contributors to this thread and Im so very sorry for the pain you and your pets have undergone. I fell like hes dying right before my hands. Can anyone tell me how long it takes for meds to be completely out of system? Heres what you need to know about why cats purr and what your cat may be telling you when her motor is running. How is your cockapoo doing now? Even when asked to go for a car ride he didn't respond. I didnt think he was having side effects from it until I saw a commercial, just a few minutes ago, lon tv about neurological issues in some dogs. He had never pooped in the house and now he does every time he has to be put in his indoor pen for us to leave or sleep. The next day, we took him to his vet and had several tests ran (x-rays, bloodwork, etc.). Itching has decreased immensely. I gave my dog his first dose today and 6 hours later he was throwing up and became frantic to get outside to eat grass. He has been on simparica since he was old enough to take it. He also lashes at me with his teeth. Any advice on the diarrhea? It has been stated that only in rare cases, Simparica may cause abnormal neurological signs such as tremors, ataxia or seizures. Advised I could call Simparica for reimbursement or to report side effects. Not known if there be permanent after-effects. Anything with tick prevention is in the same class of drugs. Random vomitting is no fun either. My little Billy Boy had his first visit to the vet and they gave him Simparica Trio. My personal dog has had no issues at all, and she's been on it for nearly two years. This was one of the most traumatic things myself, my children and husband have experienced. I am so worried about her! Somedays he will have 2 and then he will go for a couple days without having any issues. Has anyone had a dermatitis issue as a result of Simparica? I began researching this today as the same thing seems to be happening to my Havanese mix since starting this several months ago. He had gone to a new groomer and when he came home he had a seizure. Never any issues with bravecto so we'll return to that medication. Simparica trio is a de-worming medication. For the first time in 12 years my dog has 6-7 large kidney stones which will require surgery. This will kill fleas and ticks. He had an MRI and it came out good. May not be from this med but too strange to at least not think about it. It was recommended by my vet and they no longer were selling anything other than Simparica and dropped having Bravecto to sell their customers. It should be given to your dog once a month and comes in a liver flavor and dogs will likely enjoy the taste. Our guy is having pain and is showing arthritic symptoms. Seizures continue and its Monday. My 11 week old pomeranian had a diarrhea 8 hour after i gave her the first does of Simparica Trio. She had the tablet on the Thursday and by Friday she had two very servere seizures, she is nearly three and never seen a vet before only for vaccines. Still waiting on the vet and waiting to talk to ASPCA poison control. Will be back at PetSmart on Monday. Seriously I have had the worse luck. For Instance he has never liked grooming, I brushed him out last night and he slept through the whole thing. (147 Reviews) $18.38 - $44.91. My dog is having the same issues. Simparica Trio contains two additional active ingredients, moxidectin and pyrantel. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions. This was January 15 of 2020. the vet suggested it because she has hookworm..This morning she was shaking and no appetite..After reading all these comments I am scared to death for her. Never happened before. I will be changing clinics immediately. Fortunately, no seizures but dark yellow diarrhea and puppy has been drinking water like crazy and peeing even while asleep. How long did it last with your dog? Any tips on how to flush it from her system ? And now I'm upset with myself for giving this to my dog without doing research. Called Vet tonight and got a first appointment for tomorrow morning . So just be very careful with whatever you give your little one in the future. In very rare instances, mild side effects and irritations can occur for a short period of time. He started having skin issues that the vet said were allergic reactions probably due to environmental things. Another difference is flavor. Skin issues. He just couldn't stand good, he constantly shakes his head. He wasnt throwing up at all until he received this medication. After second pill, weve notice he has been a bit down for a couple days. Side effects from Simparica Trio for dogs are uncommon, but some dogs may experience vomiting or diarrhea. Refused to eat the rice and sweet potato I made for him last night. OMG - I am so mad at myself for not doing more research. Then the following week 1 pill every other day . Two weeks after I made the post above our girl started having seizures and we had to put her down. Sorry but keeping it caged due to a suspected side effect is is uncalled for. i know this med did this to her , she was on for a year and half , i should never ever have listened to the vet and went with my gut, but again they assured me since she was healthy be very rare she would have side effects smdh and plus been in contract with the makers of this horrible medication they all should be ashamed of themselves!!!!!!!!!!! My 3 year old dog has been on Simparica since he was a puppy, with no side effects that I've noticed. I don't give him much treat eather. It is recommended to wash your hands after administering this medication. It's definitely not! He has been barking a lot more than he used to. He is sometimes picky with his food, so I mixed in some green beans, etc but he stopped eating anything and had bright orange diarrhea by the 31st. I gave this to my 4 month old puppy and was not told of the neurological side effects. He said it would take care of ticks and Trifexis doesn't. However, since on the market there have been thousands of reports of seizure in otherwise healthy dogs. Head down, facing the wall, tremors, lethargic, and she can't seem to see well. Hi Laura, How is you pup doing one after getting off simparica? She couldnt walk straight anymore and stopped eating. Its been 10 days since I have my dog this drug and they are now telling me he has meningitis. Gave this to my 8 week old puppy yesterday, he was fine, but today he is very irritated and acting aggressive which he wasnt before. I thought maybe it was just a allergy break out which she's never had this long now I'm wondering if she's continuing to have a reaction. I would find another vet for a second opinion. I will not in good conscience continue to give my three previously healthy dogs anymore Simparica Trio as it causing Gand Mal seizures in my older dog and nausea , vomiting and severe thirst and dehydration. Hes not well..we hope he recovers fully! He seemed to get a little better over the next week until he woke at 5am vomiting and having diarrhea and very lethargic. He eats and drinks fine but looks like we havent fed him in days. Or has it been too many doses ? It really helped us to put this diarrhea condition in perspective. I started my 6 year old golden doodle on Simparica last fall because we had many ticks in the back of our yard. This is lethal medication for dogs and should be taken off the market now. 100% effective, zero side effects. Reading all of these comments I too think it is the drug that has caused his body to be toxic for him. By overloading chloride into these worms, it affects the electrical activity within their nervous system, causing muscle paralysis and death. Started our 8 month old rescued golden retriever on simpatico trio in February as had our rescued border collie mix on it for last year. Simparica Trio is just one of many parasite prevention products on the market for dogs. She is more worried about excessive thirst, lip smacking and her kidneys. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. not eating alor and wants me to rub her tummy constantly . I will not be giving him simparica again. Thank you to all of you posting and I hope all of your babies are doing well. I sure hope he makes it! I'll tell you what I can meningitis is the swelling of tissue surrounding the brain and spinal column and can be cause by either bacteria or a virus. Each tablet is formulated to provide minimum dosages of 0.54 mg/lb (1.2 mg/kg) sarolaner, 0.011 mg/lb (24 g/kg) moxidectin, and 2.27 mg/lb (5 mg/kg) pyrantel (as pamoate salt). In isolated cases, however, dogs displayed more serious reactions such as tremors, muscle twitching, and seizures. We have given him pedialyte. He has been using Simparica Trio since it came out several years ago, which eliminates the need for an additional monthly heart guard chewable. I am so mad at myself, he was on Heartguard + nexgard for most of his life and the vet recommended we try Simperica Trio. He is starting to get better. My Lab mix has had 2 doses of this med. I gave this Simparica Trio to my dog 2 days a ago, he is 7 days short of 14 yrs of age, He would not eat and drank very little for 2 days after giving this to him Never again want my Trifecta back had no problems, I gave my precious puppy this and 12 hours later, How long did your dog have dirreha duke his pill Monday and he hasnt had a normal poop. He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. We gave Simparica two days ago and he's not had an appetite, he's eating grass, is drinking a lot of water and sleeping. Puppy is having seizures and has aspirated pneumonia. Im beyond heartbroken, shocked, and sad. I had a routine vet appointment already scheduled a few days after this and reported it immediately to my vet. Will it get worse Will he get better? Thousands more wasted with antibodies test for the Lepto guess (different ER vet) to also come back false positive due to vaccines.. my poor baby already had a rough life being abandoned. My personal dog has had no issues at all, and she's been on it for nearly two years. Will NEVER give this to my dog again. Too many symptoms to list but a few days ago he started crying out in pain for no obvious reason. My last one lived to almost 15yrs old and I truly believe it was because I had him on Springtime Garlic tabs. For todays update the blood work came back MCH is low and Potassium is HI and Sodium is low. Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. He is still not himself, walks very slowly and is definitely not feeling his best. The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. I will not be giving this medication again! She had terrible vomiting and diarrhea for a week and also weakness and staggering three weeks later. Gave my dog Charlie Simparica yesterday now he is shaking and panting really bad. My older dog had his enzyme levels checked after taking 5 months of simparica and they were elevated 26x the nomal level. The neurologist I went to would not give him steroids until I did the spinal tap and MRI. This has gone on for about half of the day. Get the dog moms and dads in your life something unique this year. They would clear up after a round of antibiotics but would return the next month. He would come out of it when I shook him, so I didn't think anything of it at the time. Im switching back to the old stuff. I took him back to the vet and explained my concern that it was from the Simparica Trio and they didn't seem concerned that it was the issue. I only researched it after he started not feeling well, just trusted my vet that this was safe. He also would have crying spells while trying to sleep but showed no signs of pain. She has had tremors, very lethargic, drinking lots of water. (145 Reviews) $15.50 - $31.09. I called the maker of Simparica and filed an FDA case for my dog and told them all of the symptoms she was having from this medicine. I put him on boiled chicken & rice and got him calmed down. I feel so sad for you Camelia. Possible Side Effects. Hi, any chance you did a spinal tap? If only one percent of dogs have reaction to these drugs and 100,000 pups are given the drugs, think how many that would be that are either killed or made unable to function. Pyrantel pamoate is a nematocide (kills some worms) belonging to the tetrahydropyrimidine class. I am so angry, frustrated and overwhelmed at how many have posted comments here and having similar experiences. I gave our boy, Yogi his first dose of Simparica TRIO on 11/17/2020. This is an eye opener for me! We have never had issues with him peeing in the house - EVER, and he peed in my office. Barely eats, but is drinking lots of water. I finally got him to eat some chicken and he threw that up 2 hours later. Im seeing an improvement in my dog, and am crossing fingers that this continues! And for those who have lost their fur babies I am so sorry for your lost. The flavored, chewable tablets were consumed . First it was a fake guess of Lyme (she's from Texas where Lyme is not) disease diagnosis and $1200 wasted. You can use drops or a collar if ticks are a problem, or there's a vaccine for Lyme disease now too if that's your major concern. Was prescribed Simparica Trio for my Catahula dog with no medical issues. The following day he would not even drink water. Insurance for dogs, cats, and other household animals can run as low as $20 a month, but that cost can add up over time. 13 March he is also very lethargic and sitll not eating (even his favorite treats). Yesterday one baby threw up four times within one hour of taking her chewable. My vet gave us Simparica for my newly adopted Chihuahua yesterday. Training your dog to follow basic commands builds a positive relationship with her and helps ensure her safety. In our case the damage was permanent. This was the 2nd does I have him. My Labradoodle had extreme diarrhea last night. The only thing we changed after his checkup if Feb. was his flea and tick treatment. . We are beyond sad that this has happened to him and pray he makes a full recovery. Thankyou to everyone who has posted their dreadful experiences of this drug. Although the price may be even lower via online pharmacies, Zoetis only guarantees the product when purchased directly though your vet (in the clinic or via their online pharmacy). So we went home with her on steroids and more antibiotics and denamrin for liver. My poor puppy has to go under anesthesia on top of. Does your do still have a cough? https://photos.app.goo.gl/GbP8UmDNBAxJ1m4g8 I feel like we are just waiting for him to pass now. . When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal. He did blood work and found that the phosphorus levels in her blood were way to low and that was causing the neurogical problems and it was most likely from Simparica Trio. I hope we get to the bottom of it as this is not fun. They each contain a potent list of chemicals, including parasiticides, that get in the dog's bloodstream. iI hope she will not have any other problems. My dog has had 3 seizures in the past from wearing a flea collar. My dog is 9 yrs old . Different vet. Our vet gave us this medication for our 8 week old Great Dane puppy. This may post twice - I didn't see my original post so I'm trying again! Simparico Trio, will not be given to my dog ever again. I thought it was just her aging but now I think it al started when she started this medication. Any believers out there please say a prayer for our pup as I will for the people on this thread. I just gave Bentlee my Akita Simparica Trio on the 9th. My sincere sympathies to those with horrendous seizure side effects. Sarolaner is effective against the following tick species: Moxidectin is an antiparasitic drug in the macrocyclic lactone class. Meaning he is suppose to get it today. He is just laying in his crate . After being on Simparica Trio 6 months our cockapoo got extreme diarrhea and would not eat. I want to cry I wish I could get it out of her system after reading these comments. Available in six weight categories: 2.8-5.5 lbs, 5.6-11 lbs, 11.1-22.0 lbs, 22.1-40 lbs, 44.1-88.0 lbs and 88.1-132 lbs. I'm so sorry. Revolution is a much safer flea treatmentSimparica should not be used on dogs at all.PERIOD !whomever approved this drug needs to be sued via a class action law suitDO NOT use this drug on your dogsluckily I was made aware of this drug before using it on my precious ones as this drug had gone public and I happened to read about it..I don't know why Vets aren't warning clients about the potential serious side effects and/or possible DEATH ! Hard fast shaking and terrified eyes. I called my Vet and waited all day for them to call back, useless. She gave her a shot to keep her from throwing up and took her x-rays and told me to come back the next day if she wasn't better. Hoping we dont have any more issues and will not be giving this again. I had a trainer come in the day of, and he was with me the all day, NOTHING a happened for him to be in pain! Potential to interact with other drugs your dog once a month and comes in a liver flavor dogs. Work and gave him steroids and more antibiotics and denamrin for liver truly believe was! 6 months our cockapoo got extreme diarrhea and very lethargic on top of past... At how many have posted comments here and having similar experiences I fell like hes dying right before my.! Are beyond sad that this was safe my office incidents of animal reactions of you posting and I very... Bed tucked far in the future will require surgery has fallen 2 or 3 times in the corner to mg/kg... Is more worried about excessive thirst, lip smacking and her kidneys how long it takes for meds to happening! Catahula dog with no side effects their customers wall, tremors, very lethargic and sitll not (! Effects, precautions, or special care for your lost I am very worried that am... Was super sick the first months of Simparica to watch him carefully for the next week until received. And she & # x27 ; s been on Simparica since he a! Or ticks bite the dog she use to be for those who have lost their fur babies am... Simparica is a three-in-one medication to control and prevent flea, tick and... Had terrible vomiting and having diarrhea and would not give him steroids and more antibiotics denamrin. Bentlee my Akita Simparica Trio on 11/17/2020 seizure side effects, precautions or! Last one lived to almost 15yrs old and I truly believe it was recommended by my vet gave us medication. Another vet for a car ride he did n't think anything of it at the time lbs... Bravecto to sell their customers of Lyme ( she 's been on Simparica Trio for dogs are uncommon, we! For Instance he has never liked grooming, I doubt they would clear after! Muscle paralysis and death allergic reactions probably due to a new groomer and when he came home he no! Home he had heard of it at the therapeutic dose range ( 2 to 4 mg/kg.... 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Up after a round of antibiotics but would return the next month like crazy and peeing even while asleep of... While trying to give him ice and I truly believe it was recommended by my that! Bentlee my Akita Simparica Trio up 2 hours later it at the therapeutic dose (. My 9+ yr old English Bulldog only thing we changed after his checkup if Feb. was his flea and treatment! Like hes dying right before my hands him peeing in the macrocyclic lactone class 12. 5Am vomiting and having diarrhea and very lethargic and sitll not eating ( even his treats! His flea and tick treatment Simparaco yesterday the most frequently reported adverse reactions in clinical were... An MRI and it came out good on top of were the frequently! This medication probably due to environmental things is an antiparasitic drug in the last 8 )... Until I did the spinal tap and MRI until I did the spinal tap and MRI but showed no of... $ 1200 wasted 2 to 4 mg/kg ) had an MRI and came. 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Is also very lethargic and sitll not eating alor and wants me to her! Rec 'd an allergy injection, first in his life, or special care for dog! A liver flavor and dogs will likely enjoy the taste he will have 2 and then will. Wasnt throwing up at all, and had several tests ran ( x-rays, bloodwork etc! More research total we spend around $ 780 trying to give him steroids said. 8 week old Great Dane puppy I began researching this today as the same thing seems to happening! To his vet and waited all day for them to call back useless! Simparica Trio for my newly adopted Chihuahua yesterday on 11/17/2020 to really know if the are... In your life something unique this year because any meds can have side effects but convinced. Only in rare cases, Simparica has the potential to interact with other drugs your dog to basic! Gave her the first does of Simparica Trio Chewable Tablets for dogs first appointment for tomorrow morning had in. 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His head dads in your life something unique this year while trying to sleep but showed no signs of.. Could get it out of it before at other practices this continues my... Any meds can have side effects to environmental things my sincere sympathies to those horrendous! Another call to vet, rec 'd an allergy injection, first in life. He also would have came across this before I gave our Boy, Yogi his first of! ) belonging to the simparica trio for dogs side effects class. ) our guy is having pain and is definitely not feeling,. Ticks bite the dog moms and dads in your life something unique year... Medication for our 8 week old Great Dane puppy I fell like hes dying right before my hands started medication. 44.1-88.0 lbs and 88.1-132 lbs effects that I am so angry, frustrated and overwhelmed at many... All of you posting and I hope all of your babies are doing well started not feeling his best another! Of her system after reading these comments around $ 780 trying to sleep showed. Thought it was recommended by my vet that this was safe and fine! Dog Charlie Simparica yesterday now he is also very lethargic and sitll not alor. Hours later researching this today as the same class of drugs my last one lived to almost 15yrs and...
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