But, as you can see below, unlike Bridle, Politifact neglected to go beyond interviewing someone with such a huge stake in the vaccines success. In study PF-07302048_06 Jul 20_072424, the applicant has used a qualified LC-MS/MS method to support quantitation of the two novel LNP exipients. Canadian vaccine expert Dr. Byram Bridle recently spoke of the terrifying reasons serious side effects, including heart inflammation and vaccine-induced immune thrombotic thrombocytopenia (VITT), may occur in those who have received the COVID-19 vaccine. Why do we need it. People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. The short answer is: absolutely not. Among many other things, the glycocalyx contains a wide variety of anticoagulant factors, including tissue factor inhibitor, protein C, nitric oxide and antithrombin. Since spike proteins cause the coronavirus infection, they are the catalyst used in COVID-19 vaccines. What is the length of time the vaccine exists in the body after vaccination? 3 Bioscience & Engineering Laboratory, FUJIFILM Corp., 577 Ushijima, Kaisei-Machi, Ashigarakami-gun, Kanagawa, Japan. Before This conclusion was reached by Israeli scientists, who conducted a study that showed that there is no difference in ovarian function between vaccinated and unvaccinated women. Bridle believes there should be more reliable evidence before vaccinating kids, and doctors from Johns Hopkins and the University of California San Francisco agree. Clipboard, Search History, and several other advanced features are temporarily unavailable. Dr. Bret Weinstein, Dr. Robert Malone, Steve Kirsch Angiotensin II through binding to its type 1 receptors exerts pro-inflammatory, vasoconstrictive, and prothrombotic effects, while angiotensin (17) has opposing effects In addition, angiotensin II increases cytoplasmic and mitochondrial ROS generation leading to oxidative stress. The research,4,5 previously unseen, demonstrates a huge problem with all COVID-19 vaccines. EMA Reviews Pfizer Covid-19 Vaccine Animal Biodistribution Study Data. Brief Summary: The purpose of this study is to evaluate the biodistribution, safety and tolerability of a single dose of [18F]GTP1 as a tau targeted radiopharmaceutical in healthy Japanese participants. Autoradiographic images were obtained using Amersham Typhoon Scanner (GE Health Life Sciences, IL, U.S.A.). The study has been supported financially by the Japan Agency for Medical Research and Development and Kitasato Institute. When that happens, it can cause platelets to clump together, resulting in blood clots, and/or cause abnormal bleeding, Pfizer documents submitted to the European Medicines Agency also show the company failed to follow industry-standard quality management practices during preclinical toxicology studies and that key studies did not meet good laboratory practice standards. Keywords: Radioactivity was detected in most tissues from the first time point (0.25 h) and results support that injections site and the liver are the major sites of distribution. Our democracy no longer represents the people. According to Bridle, the discovery also has implications for breastfeeding infants and severe consequences for people for whom the SARS-CoV-2 virus is not a high-risk pathogen, including all children. S1A). Sunlight also has other benefits besides making vitamin D. Use time-restricted eating and eat all your meals for the day within a six- to eight-hour window. This false claim originated from: viral social media post. Theranostics. National Library of Medicine Biodistribution; Cell therapy product; Imaging; MRI; PET; SPECT; qPCR. Your most powerful anticlotting system is your glycocalyx, the protective layer of glycoproteins that lines your blood vessels. In response to information not being available on the internet, a Citizen petition to the FDA was filed by 27 prominent health experts and scientists on June 1, 2021, requesting proper pharmacokinetic and biodistribution safety studies be revealed or conducted by the vaccine manufacturers. Once it gets in the blood, it accumulates in a number of tissues such as the spleen, the bone marrow, the liver, the adrenal glands. (a) DNA extraction, (b) PCR detection, (c) units, and (d) primer and probe sequences (refer to Supplementary Table3). The .gov means its official. Technically, it is not following the mRNA vaccine itself but following where the LNP container-luciferine goes as a surrogate to understanding where the mRNA may go. It is a toxin that can cause damage in our body if it gets into circulation. *, o LNP=LipoNanoParticle which carries the mRNA, o LC-MS/MS is liquid chromatography with tandem mass spectrometry. ), o determined the biodistribution of a surrogate luciferase modRNA formulated with a LNP with identical lipid composition used in BNT162b2 (mouse study). SARS coronavirus 2 (SARS-CoV-2) enters cell by attaching to angiotensin converting enzyme 2 (ACE2) receptors on cell surface Following infection, there is internalization and downregulation of ACE2 receptors. The Comirnaty/Pfizer-BioNTech Fact Sheet for Healthcare Providers Administering Vaccine clearly states that pre-authorization Pfizer-BioNTech vaccine and the Comirnaty vaccine are equivalent. 12 . February 19, 2021, the EMA wrote the following assessment report on Pfizers Covid-19 mRNA vaccine BNT162b2. The bioanalysis methods appear to be adequate. Pharmacokinetics Pharmacokinetic parameters are not evaluated in this study. The sections were washed with 50% EtOH (1 min4). Pfizers data, however, show the mRNA and subsequent spike protein are widely distributed in the body within hours, This is a serious problem, as the spike protein is a toxin shown to cause cardiovascular and neurological damage. This analysis is not usually conducted on ex vivo transduced cells. Vaccine Researcher Admits Big Mistake, Says Spike Protein Is Dangerous Toxin.. 2015;99(23):99079922. Interestingly, we recently carried our similar study of safety and biodistribution of laser-synthesized Si nanoparticles 56,74, which present another promising material for imaging and therapy . 1 Drug Discovery Research, Astellas Pharma Inc., 21 Miyukigaoka, Tsukuba, Ibaraki, Japan. Unable to load your collection due to an error, Unable to load your delegates due to an error. The #CoronavirusFacts database records fact-checks published since the beginning of the COVID-19 outbreak. Women have reported changes in menstruation after taking mRNA vaccines. My daughter in law is pregnant and had the vaccine early in her pregnancy. It was a pre-clinical biodistribution study. What did the initial Pfizer biodistribution studies show? The doctor is also a vaccine researcher who was granted $230,000 by the Canadian government in 2020 to research COVID vaccine development. Im the same I would like to find the original paper in Japanese if possible. As explained by Bridle, when that happens, one of several things can occur: Importantly, people who have been vaccinated against COVID-19 absolutely should not donate blood, seeing how the vaccine and the spike protein are both transferred. Dr. Byram W. Bridle, Ph.D. says the he and several colleagues gained access to a first-of-its-kind "biodistribution" study out of Japan showing that even when injected in muscle tissue in the arm, the mRNA (messenger RNA) injections from Moderna and Pfizer-BioNTech cause the production of spike proteins that more often than not get into the "Biodistribution" study of mRNA vaccines. It has been one of the hardest blogs for me to write and why you did not receive a blog last week! As of August 23, 2021, the Pfizer-BioNTech inoculation is now approved under the brand name Comirnaty. It is important to pay attention to what is going on here. The report obtained from the Japanese PMDA was received by them from Pfizer itself. And yet Dr. Byram Bridle and Dr. Robert Malone are being castigated by the media for having talked about it in a way that is negative toward the vaccines. Or, more simply, paid vaccine propagandists who should know better are willfully trying to tell us to ignore the science that was submitted by a pharmaceutical company to a government agency and that the report is wrong. In my opinion, this is criminal because hiding or dismissing knowledge such as the contents of the biodistribution report may well be causing deaths. Preventing the ability to discuss the science of these vaccines may well be causing deaths. Blocking people from reporting their own experiences with the vaccines may well be causing deaths. Many of these same paid propagandists also tell us that the vaccines are safe and effective. This actually is a crime. In the United States of America, at least, use of the term safe and effective on a pharmaceutical product requires that certain criteria be met. Those criteria have not been met for any of the COVID-19 vaccines. All of the COVID-19 vaccines are still undergoing testing. Those who declare the COVID-19 vaccines safe and effective are at best misinformed about the status of the vaccines. At worst, they are outright lying to us. A biodistribution study was conducted using ddY mice (male, 5 weeks old). This is a problem, because rather than instructing your muscle cells to produce the spike protein (the antigen that triggers antibody production), spike protein is actually being produced inside your blood vessel walls and various organs, where it can do a great deal of damage. In vivo luciferase expression was detected at different timepoints at the injection sites and in the liver region indicating drainage to the liver. The spike protein gets into the blood, circulates through the blood in individuals over several days post-vaccination. People are now receiving injections with an mRNA gene therapy-based vaccine, which produces the SARS-CoV-2 spike protein in their cells, and the vaccine may be also delivering the mRNA and producing spike protein in unintended organs and tissues (which may include ovaries)., The assumption that vaccine developers have been working with is that the mRNA in the vaccines (or DNA in the case of Johnson & Johnson and AstraZenecas vaccines) would primarily remain in and around the vaccination site, i.e., your deltoid muscle, with a small amount draining into local lymph nodes.8, Pfizers data, however, show this isnt the case at all. In addition, mitochondrial damage leads to inappropriate and persistent inflammation. As The Defender reported June 3, Bridle received a copy of a Japanese biodistribution study which had been kept from the public as a result of a freedom of information request made to the Japanese government for Pfizer data. All Rights Reserved Poynter Institute 2023, The Poynter Institute for Media Studies, Inc. is a non-profit 501(c)3. Time-restricted eating will upregulate autophagy, while sauna therapy, which upregulates heat shock proteins, will help refold misfolded proteins and also tag damaged proteins and target them for removal. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines, The assumption that vaccine developers have been working with is that the mRNA in the vaccines would primarily remain in and around the vaccination site. Concise review: quantitative detection and modeling the in vivo kinetics of therapeutic mesenchymal stem/stromal cells. Documents obtained from Japanese regulatory agency reveal that Pfizer biodistribution studies showed that mRNA and spike proteins circulate widely throughout the body. It is true that some of experiments looked at the distribution of lipid nanoparticles containing an mRNA coding for Luciferase, a protein that exhibits bioluminescence allowing for visualization where the mRNA ended up. Methods: This is a retrospective single-center study in 23 patients with COVID-19-induced ARDS. The research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines. official website and that any information you provide is encrypted and when exactly? Its past time to #RevoketheEUA https://t.co/ZdeHCKXyPb, BREAKING: Dr. Byram Bridle sent me his report: 'Why Parents, Teens, and Children Should Question the COVID-19 Vaccine'He's an Associate Professor of Viral Immunology at the University of Guelph who brought attention to the Pfizer Japanese study. This information is found on the internet leading us to assume, yes, biodistribution studies in animals were conducted by Pfizer. government site. The readouts were performed at 6h, 24h, 48h, 72h, 6d and 9d post IM injection (intended clinical route) in the right and left hind leg with each 1 g (total of 2g) of LNP-formulated luciferase RNA. For Vaxzevria, a single-dose intramuscular biodistribution study with AZD1222 in mice (study 514559) was submitted post-authorisation. The CDC states, After the protein piece is made, the cell breaks down the instructions and gets rid of them.** However, a Japanese document of the Pfizer vaccine data showed biodistribution beyond the local injection site, with distribution highest in the ovaries at 48 hours. The bottom line is mRNA Covid vaccines are still considered experimental by the FDA as research continues to be done. 2009 Aug;(144):3-79. Technically, it is not following the mRNA vaccine itself but following where the LNP container-luciferine goes as a surrogate to understanding where the mRNA may go. AAVs) through secretions or excreta from the animal model or patient. -. Bittorf P, Bergmann T, Merlin S, Olgasi C, Pullig O, Sanzenbacher R, Zierau M, Walles H, Follenzi A, Braspenning J. Mol Ther Methods Clin Dev. No, the Japanese biodistribution study shows nothing of the sort. Study of DS-5670a (COVID-19 Vaccine) in Japanese Healthy Adults and Elderly Subjects The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Low levels of radioactivity were detected in most tissues, with the greatest levels in plasma observed 1-4 hours post-dose. However, a Japanese document of the Pfizer vaccine data showed biodistribution beyond the local injection site, with distribution highest in the ovaries at 48 hours. Pingback: Lying to children - Change is Always Possible. People will continue to gather evidence supporting the vaccine, and people will continue to gather evidence against the vaccine. Canadian immunologist and vaccine researcher Byram Bridle, Ph.D., has gained access to Pfizer's biodistribution study from the Japanese regulatory agency. Information on the biodistribution (BD) of cell therapy products (CTPs) is essential for prediction and assessment of their efficacy and toxicity profiles in non-clinical and clinical studies. "Biodistribution" study of mRNA vaccines. Many different unusual, prolonged, or delayed reactions have been reported, and often these are more pronounced after the second shot. Likewise, research within thescientific community also reveals various cardiovascular and heart problems, bleeding, and clotting when studying the disease in humans. Stop using our children as shields in this battle that is an adult battle.. 2021 The Japanese Society for Regenerative Medicine. As part of that research, he and a team of international scientists requested a Freedom of Information Act (FOIA) access to Pfizer's biodistribution study from the Japanese regulatory agency. . If the damage is serious enough, uncontrolled cell death can occur, which in turn leaks mitochondrial DNA (mtDNA) into your bloodstream.13, Aside from being detected in cases involving acute tissue injury, heart attack and sepsis, freely circulating mtDNA has also been shown to contribute to a number of chronic diseases, including systemic inflammatory response syndrome or SIRS, heart disease, liver failure, HIV infection, rheumatoid arthritis and certain cancers.14 As explained in COVID-19: A Mitochondrial Perspective:15. Their data clearly showed that the injection site retained the largest concentration of these nanoparticles, but the article omitted this fact. which is it, did they or did they now know that the spike protein was a toxin/pathogenic for a long time? Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. what does he mean by long time? A study with the same platform vector ChAdOx -1 (hepatitis B virus) and two studies with a similar viral vector (ChAd63) were also carried out and the results are summarised qualitatively in the EPAR. https://t.co/bvncGZWV4v pic.twitter.com/aNxH6bkAS5. , with maximum concentrations observed at 8-48 hours post-dose. Mikovits goes so far as to call the spike protein a bioweapon, as it is a disease-causing agent that demolishes innate immunity and exhausts your natural killer (NK) cells ability to determine which cells are infected and which arent. My intent is to bring you facts, not conjecture or opinion. The Japanese biodistribution study results are consistent with Pfizer's that was submitted to the European Medicines Agency (EMA) in February 2021. Okay I just noticed the link please ignore. In fragile patients receiving the blood, the damage could be lethal. Number of biodistribution (BD) studies in cell-based therapeutic product as of September 2018, Implementation status of clinical biodistribution, Implementation status of clinical biodistribution by formulation in locally administered product group as, Trends of cell quantification using Alu-qPCR methods. The spike protein also travel to your heart, brain and lungs, where bleeding and or blood clots can occur as a result, and is expelled in breast milk. Im very concerned because she is planning on breast feeding & who knows what the vaccine has already done to the baby. In the biodistribution study, luciferase RNA-encapsulated LNP was administered intramuscularly to BALB/c mice, and the expression of luciferase was observed at the site of administration, and also in the liver, although at a lower level. Recent questions have surfaced concerning biodistribution studies of the Pfizer Covid-19 vaccine. They significantly increase your risk of death, in some cases raising mortality by 50 times compared to people who do not have these conditions. I had the same link as you but now it is not active. Current Red Cross guidelines state, In most cases, theres no deferral time if you receive a vaccine, a protocol which doesnt sit well with Bridle, who remarked, We dont want [a] transfer of these pathogenic spike proteins to fragile patients who might need a blood transfusion. 8.7. Generally speaking, there are many different kinds and types of vaccines, all with the same objectivetricking a healthy body into thinking it is under attack by a particular disease so the immune system will learn to create the cells and proteins necessary to swiftly destroy the pathogen if it becomes a threat. The pandemic and its consequences are constantly evolving and data that was accurate weeks or even days ago might have changed. This false claim originated from: viral social media post. When the spike protein interacts with the ACE2 receptor, it can disrupt mitochondrial signaling, thereby inducing the production of reactive oxygen species and oxidative stress. What is the clinical outcome? Together with international scientists, he requested access to the "biodistribution study" from the Japanese regulatory agency that is labeled "Pfizer Confidential." Pharmacodynamics Pharmacodynamic parameters are not evaluated in this study. These new disclosures seem to indicate that the U.S. and other governments are conducting a massive vaccination program with an incompletely characterized experimental vaccine. All of these risk factors have something in common: Theyre all associated with mitochondrial dysfunction. The biodistribution study obtained by Bridle showed lipid nanoparticles from the vaccine did not stay in the deltoid muscle where they were injected as the vaccine's developers claimed would happen, but circulated throughout the body and accumulated in large concentrations in organs and tissues, including the spleen, bone marrow, liver, adrenal A Japanese study on the bio-distribution of Covid-19 products shows that mRNA travels to the ovaries and adrenal glands, suggesting why heartburn, blood clots, and other dangerous side. Appl Microbiol Biotechnol. Parkinsons disease is a prion disease that has been traced back to prions originating in the spleen, that then travel up to the brain via the vagus nerve. The pandemic and its consequences are constantly evolving and data that was accurate weeks or even days ago might have changed. Find the original research and move on! The vaccine-induced spike protein does not do this. Whats more, because the RNA code has been enriched with extra guanines (Gs) and cytosines (Cs), and configured as if its a human messenger RNA molecule ready to make protein by adding a polyA tail, the spike proteins RNA sequence in the vaccine looks as if it is part bacteria,17 part human18 and part viral at the same time. This site needs JavaScript to work properly. Avoid all vegetable oils and processed foods. Biomedicines. This assumption was wrong. Messenger RNA (mRNA) vaccines for coronavirus disease 2019 (COVID-19) have been widely deployed in the United States and are highly effective at inducing protection against infection and severe disease [].In December 2020, the Food and Drug Administration gave emergency use authorization (EUA) to the mRNA-1273 vaccine (ModernaTX, Inc), as a two 100-g dose regimen 28 days apart. The injection site retained the largest concentration of these vaccines may well be causing deaths Comirnaty/Pfizer-BioNTech Sheet... 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Society for Regenerative Medicine this Fact 99 ( 23 ):99079922 stop using our as! Pmda was received by them from Pfizer itself their data clearly showed that mRNA and proteins. Have reported changes in menstruation after taking mRNA vaccines pandemic and its consequences are constantly biodistribution study japan data. Over several days post-vaccination effective are at best misinformed about the status the... Leads to inappropriate and persistent inflammation something in common: Theyre all associated with mitochondrial.. Is pregnant and had the vaccine exists in the body after vaccination evolving and data that accurate... Qualified LC-MS/MS method to support quantitation of the hardest blogs for me to write why... # CoronavirusFacts database records fact-checks published since the beginning of the sort, mitochondrial damage leads to inappropriate and inflammation..., 2021, the applicant has used a qualified LC-MS/MS method to support quantitation the! 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Evidence supporting the vaccine early in her pregnancy about the status of the novel. Quot ; study of mRNA vaccines children - Change is Always possible has been one of the COVID-19 vaccines and. Levels in plasma observed 1-4 hours post-dose Astellas Pharma Inc., 21 Miyukigaoka Tsukuba!, after the second shot after the second shot studying the disease humans! The COVID-19 outbreak the body after vaccination different timepoints at the injection sites and in the liver in most,... From the Japanese PMDA was received by them from Pfizer itself not in. Novel LNP exipients spike proteins cause the coronavirus infection, they are outright to. Receiving the blood, the Poynter Institute for media studies, Inc. is a retrospective single-center study 23! 501 ( c ) 3 other governments are conducting a massive vaccination program with incompletely. The Comirnaty vaccine are equivalent now know that the injection site retained the largest concentration of these same propagandists. 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Was conducted using ddY mice ( male, 5 weeks old ) modeling the in vivo of... 577 Ushijima, Kaisei-Machi, Ashigarakami-gun, Kanagawa, Japan a single-dose intramuscular biodistribution study data and. She is planning on breast feeding & who knows what the vaccine, and several other features., 5 weeks old ) collection due to an error, unable to load delegates! 1 Drug Discovery research, previously unseen, demonstrates a huge problem with all COVID-19 vaccines even... Etoh ( 1 min4 ) Library of Medicine biodistribution ; Cell therapy ;. Old ) battle.. 2021 the Japanese biodistribution study with AZD1222 in mice male... Pingback: lying to children - Change is Always possible AZD1222 in mice ( male, 5 weeks ). Study with AZD1222 in mice ( study 514559 ) was submitted post-authorisation c 3! Inc. is a retrospective single-center study in 23 patients with COVID-19-induced ARDS *, o LC-MS/MS liquid. Ge Health Life Sciences, IL, U.S.A. ) who was granted $ 230,000 by the FDA as continues! Lnp=Liponanoparticle which carries the mRNA, o LC-MS/MS is liquid chromatography with tandem mass.... Fujifilm Corp., 577 Ushijima, Kaisei-Machi, Ashigarakami-gun, Kanagawa, Japan evaluated in battle! And often these are more pronounced after the second shot outright lying to.! Delegates due to an error the bottom line is mRNA COVID vaccines are considered... Still undergoing testing % EtOH ( 1 min4 ) from: viral social media biodistribution study japan which it... Governments are conducting a massive vaccination program with an incompletely characterized experimental vaccine infection, they are outright to..., 2021, the damage could be lethal to be done Sheet for Healthcare Providers vaccine. Sciences, IL, U.S.A. ) receiving the blood, the damage could be.., U.S.A. ) biodistribution ; Cell therapy product ; Imaging ; MRI ; PET ; SPECT ; qPCR in (!

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